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- W2390324561 abstract "Objective To observe the effect of the herb formula on the expression of PDGF-B mRNA of the rabbits after percutaneous transluminal angioplasty (PTA). Methods Dividing the 54 rabbits into the bogus operation group, the model control group and the traditional chinese medicine (TCM) prevent group randomly. Replicating the animal model with once injury by balloon. Taking the material at the first week, the second week and the fourth week after the operation. HE dyeing to analyze the pathological morphologic quantificationally. Analyzing the express of the PDGF-B mRNA half-quantificationally by the PCR. Results Compared with the bogus operation group, the abnormal of pathologic picture and ultrastructure and the restenosis degree of carotid aggravated significantly of the model control group and the TCM prevent group. And their sum of the endangium and the tunica media accretived significantly. Contrasted with the model control group, the luminal area accretived significantly. Its restenosis degree of the carotid and the sum of the endangium and the tunica media decreased. But the degree of the expression of the PDGF-B mRNA of the TCM prevent group is increased obviously at the first week and the second week. Conclusion The formula of YiQiWeiYang and HuoXueHuaYu to dissipate blood stasis can restrain proliferation of the smooth muscle cells and the restenosis after PTA by adjusting the expression of the PDGF-B mRNA of vascular wall." @default.
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- W2390324561 date "2006-01-01" @default.
- W2390324561 modified "2023-09-22" @default.
- W2390324561 title "Effects of the formula of YiQiWenYang and HuoXueHuaYu on expression of PDGF-B mRNA to restenosis of rabbits after percutaneous transluminal angioplasty" @default.
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