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- W2390413013 abstract "Objective It is to observe the characteristic of apoptosis and characteristic changes on phospholipids in white matter of occipital lobe and cerebellum in heroin spongiform leukoencephalopathy(HSLE).Methods 4 cases of HSLE and 6 cases of normal corpse were autopsied and researched with the terminal deoxynucleotide transferase-mediated deoxyuridine 5-triphosphate nick-end labeling(TUNEL) method and acid hematein staining.The apoptosis and the changes of phospholipids in white matter of occipital lobe and cerebellum were detected.Results TUNEL positive cells were observed obviously in the deep white matter in HSLE relative to those in the shallow white matter(t=43.64,P0.01) and the normal control.The phospholipids stain in white matter and gray matter of occipital lobe and cerebellum in normal brains showed dark blue and yellow brown respectively,while the phospholipids stain in white matter of occipital lobe and cerebellum in HSLE showed significantly lower than that in normal brains.Apoptosis has a correlation with the phospholipids loss.Conclusion The phenomena of apoptosis and the phospholipids loss are existed in the deep white matter in HSLE.The phospholipids loss might be involved in the apoptosis and the etiology of HSLE." @default.
- W2390413013 created "2016-06-24" @default.
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- W2390413013 date "2007-01-01" @default.
- W2390413013 modified "2023-09-23" @default.
- W2390413013 title "Study of apoptosis and phospholipids changes in heroin spongiform leukoencephalopathy" @default.
- W2390413013 hasPublicationYear "2007" @default.
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