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- W2390490105 abstract "Objective:To investigate the effect of fructose-1,6-diphosphato (FDP)on myocardial injure induced by anthracycline in children with acute leukemia. Methods: 62 cases of acute leukemia with myocardial injure induced by anthracycline were assigned to 2 groups randomly. The observed group (n=32) was treated with FDP, and the control group with large doses of vitamin C, vitamin E and coenzyme Q10. Both groups were examined with cardiogram, myocardial enzymes and ultrasonic cardiogram pre- and post-therapy. Results: The levels of myocardial enzymes in both groups were decreased significantly after therapy (P＜0.001), and the difference between pre- and post-therapy in the observed group was obviously larger than that in the control group(P＜0.05). The overall effective rate in observed group was 84.4% vs only 70.0% in the control group(P＜0.05). Conclusions: Both FDP and vitamin C, E and coenzyme Q10 showed good effects on myocardial injure induced by anthracycline, but the former was better." @default.
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- W2390490105 date "2005-01-01" @default.
- W2390490105 modified "2023-09-23" @default.
- W2390490105 title "The Effect of Fructose-1, 6-diphosphate on MyocardialInjure Induced by Anthracycline" @default.
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