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- W2390497499 abstract "Objective To study the nutrient effect of glutamine-enriched parenteral nutrition on rats' spleen of acute radiation enteritis. Methods Nineteen SD rats were used, which received whole abdominal radiation. The animals were randomly divided into three groups. Standard total parenteral nutrition (STD group, n=6) and glutamine-enriched total parenteral nutrition (GLN group, n=7) was used from intravenous infusion continuously for 7 days, and Normal nonirradiated animals (n=6). The samples of spleen from these animals were taken after intravenous injection 5-bromodexyridine(Brdu) via internal vena for 1 hour. The histological changes of spleens and bromodexyridine labelled cells were studied by using light microscopy. The microstructure changes of spleen lymphocytes were studied by using transmission electron microscopy(TEM). Results The lymphocytes of white pulp, periarterial lymphatic sheath and spleenic nodule of GLN group increased compared with those of STD group. The BrdU labelled cells of the spleenic lymphocytes in GLN group were significantly more than that of STD group. Under TEM, the lymphocytes of spleen of GLN group revealed that the chromatin agglutinated and the heterochromatin decreased, the mitochondria and the rough endoplasmic reticulum increased, and the mitochondria had a little swollen compared with those of STD group. Conclusion Glutamine-enriched parenteral nutrition can improve the spleen lymphocytes proliferating and maintain the spleenic structures after abdominal radiation." @default.
- W2390497499 created "2016-06-24" @default.
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- W2390497499 date "2008-01-01" @default.
- W2390497499 modified "2023-09-25" @default.
- W2390497499 title "The effects of glutamine-enriched parenteral nutrition on rats’spleens of acute radiation enteritis" @default.
- W2390497499 hasPublicationYear "2008" @default.
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