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- W2390527867 abstract "Objective:This study was designed to evaluate the effect of dexmedetomidine on the acute hyperdynamic response,duration of seizure activity and recovery times in patients undergoing electroconvulsive therapy(ECT).Methods:Eighteen patients underwent a total of 108 ECT sessions as a crossover design.Patients were randomly allocated to receive either dexmedetomidine(1.0 μg/kg-1 IV over a period of 10 min) or saline 20 ml(control).Anaesthesia was induced with 1% propofol 1.2 mg/kg-1 IV and succinylcholine 1 mg/kg-1 IV.ECG,HR,MAP,the duration of seizure and recovery were observed.Results: HR and MAP in the dexmedetomidine groups were lower than those in the control group at 0,1,3 min after the seizure ended.Both motor and electroencephalography(EEG) seizure duration in the control group were similar to those in the dexmedetomidine groups.Conclusion:A dexmedetomidine dose of 1.0μg/kg-1 IV administered over 10 min before the induction of anaesthesia with propofol may be useful in preventing the acute hyperdynamic responses to ECT without altering the duration of seizure activity and recovery time." @default.
- W2390527867 created "2016-06-24" @default.
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- W2390527867 date "2012-01-01" @default.
- W2390527867 modified "2023-09-23" @default.
- W2390527867 title "The Effect of Dexmedetomidine on Cardiovascular Response to Modified Electroconvulsive Therapy" @default.
- W2390527867 hasPublicationYear "2012" @default.
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