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- W2390550617 abstract "Objective To investigate the protective effects of Ganfule on rats chemical liver fibrosis induced with CCl4. Methods The liver fibrosis model was established by injecting CCl4 in rats. To treat with Ganfule(3.5, 7.0 mg·kg-1) for 9wks and use Qiang Gan capsule as the positive control drug. The serum activities of AST and ALT were estimated by spectrophotometer using commercially available kits. HA,LN,PCⅢ contents in serum were quantified by radio immunoassay. Hyp production in liver tissues was measured by chemistry assay. The pathologic changes of liver tissues were observed by lightmicroscope. Results Ganfule (3.5, 7.0 mg·kg-1)could remark inhibit the activity of ALT and AST. Ganfule had the effects of reducing HA?LN?PCⅢ in serum and Hyp production in liver tissues. The liver injury of Ganfule groups on pathology was lighter than that in model group. Conclusion Ganfule has the protective effect on rats chronic liver injury." @default.
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- W2390550617 date "2007-01-01" @default.
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- W2390550617 title "Effects of Ganfule on rats liver fibrosis induced by CCl_4" @default.
- W2390550617 hasPublicationYear "2007" @default.
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