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- W2390555783 abstract "On soaking in 0.7 M thiourea dissolved in Ringer,in some 15 minutes, the toad sartorius muscle lost its responsiveness to stimulation.After return to normal Ringer,its ability to give electrical response both to direct and to indirect stimulation could be largely restored,though,as judged by the values of the resting and action potentials,the recovery found was never quite complete.However,while the electrical excitability returned,there was no corresponding recovery of contractility:even after transferring the muscle back to normal Ringer for more than 30 hours,it still could not give any contractile response either to electrical stimulation or to potassium chlo- ride depolarization.Futhermore,thiourea could also abolish the ability of the glyceri- nated muscle fibers to shorten under the action of ATP.These results indicate that thiourea probably has direct action on the contractile protein system." @default.
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- W2390555783 date "1965-06-01" @default.
- W2390555783 modified "2023-09-26" @default.
- W2390555783 title "THE SEPARATION OF EXCITATION FROM CONTRACTION IN TOAD SKELETAL MUSCLE BY THIOUREA" @default.
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