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- W2390716810 abstract "Objective To study the effects of damaged kidney function and hemodialysis treatment on the serum concentrations in patients with chronic kidney disease. Methods Ninty-two nondialysis patients with chronic kidney disease were divided into three groups according to their creatinine cleareace (Ccr) level: Ccr ≤ 30 mL/min group(Group Cr1), 30 mL/min Ccr 60 mL/min group(Group Cr2) and Ccr ≥ 60 mL/min group(Group Cr3). In addition, 25 hemodialysis uremic patients (Ccr≤10 mL/min) and 28 nondialysis uremic patients on similar bind levels of Ccr were taken as dialysis control group and nondialysis control group. The serum concentrations of tumor markers such as CEA, AFP, CA19-9, CA125 and CA72-4 were tested by electro-chemiluminescent immunoassay. Results The serum concentrations of CEA in Cr1 group were significantly higher than that in Group Cr2 and Group Cr3(all Ρ 0.05), however, the CA19-9 level in Group Cr3 was significant lower than that in both Group Cr1 and Group Cr2 (all Ρ 0.05). The serum level of CA125 in hemodialysis patients was significant higher than that in nondialysis patients (Ρ0.05). Conclusions The serum concentrations of CEA and CA19-9 increase remarkably in patients with severely damaged renal function, while, the hemodialysis treatment may enhance serum level of CA125 so that their diagnostic value for the corresponding tumors can be cut down." @default.
- W2390716810 created "2016-06-24" @default.
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- W2390716810 date "2008-01-01" @default.
- W2390716810 modified "2023-09-24" @default.
- W2390716810 title "Effects of damaged kidney function and hemodialysis on serum concentrations of tumor markers" @default.
- W2390716810 hasPublicationYear "2008" @default.
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