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- W2390725406 abstract "Objective To study the expression and clinical significance of Cyclin D1 in the colorectal cancer and proximal intestine tissues 5cm and 10cm away from the tumor.Methods To detect the Cyclin D1 in 45 cases of colorectal cancer and intestines 5cm and 10 cm away from the tumor.Results The expression of Cyclin D1 was inversely proportional to the degree of tumor differentiation.The positive rate of Cyclin D1 in patients with lymphatic metastasis and patients without lymphatic metastasis were 72.2% and 44.4% respectively.There were significant differences between the two groups(P0.05).The positive rate of Cyclin D1 in the colorectal cancer and intestines 5cm and 10cm away from the tumor were 24/45(53.3%),1/45(2.2%),and 0/4(0 %) respectively.There were significant differences between the former and the latter two(P0.01,P 0.01).The above-mentioned data had statistical significance.Conclusions Cyclin D1 participated the differentiation and development of cancer cells;and it had significant difference at different distance from the tumor in intestine tissues.Cyclin D1 can be used as one of the auxiliary indicators in the treatment and prognosis of colorectal cancer." @default.
- W2390725406 created "2016-06-24" @default.
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- W2390725406 date "2012-01-01" @default.
- W2390725406 modified "2023-09-23" @default.
- W2390725406 title "The Expression and Clinical Significance of Cyclin D1 in the Colorectal Cancer and Proximal Intestine" @default.
- W2390725406 hasPublicationYear "2012" @default.
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