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- W2390781355 abstract "With the increases of incidence year by year,alcoholic liver disease( ALD) constitutes a serious threat to human health and social development. Thus, it has been always a world-concerned disease. The pathogenesis of ALD is very complex. Early research on the pathogenesis of ALD mainly focused on the related inflammations caused by malnutrition,endotoxinactivated kupffer cells and the inflammations are also caused by oxidative stress and glutathione depletion in metabolic process of ethanol. However,it is discovered from recent studies that the intestinal flora disturbance,cytokines,immune response and multiple signal transduction pathways such as lipid metabolism, liver regeneration and apoptosis and antioxidant in liver are some of the factors involved in the development of ALD. This article presents the latest research on pathogenesis of ALD." @default.
- W2390781355 created "2016-06-24" @default.
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- W2390781355 date "2014-01-01" @default.
- W2390781355 modified "2023-09-26" @default.
- W2390781355 title "Research progress on pathogenesis of alcoholic liver disease" @default.
- W2390781355 hasPublicationYear "2014" @default.
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