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- W2390816148 abstract "OBJECTIVE To investigate the drug resistance of Escherichia coli(E.coli),the prevalence of the disinfectant-resistant genes qacE△1-sul1 in ESBLs-producing E.coli so as to announce the drug resistance mechanism of E.coli.METHODS A total of 3688 strains of E.coli were analyzed for the drug resistance to 15 kinds of antibiotics such as aminoglycoside,β-lactams and quinolones by using VITEK-32 GNS-448 cards following GNI+ cards for the identification,which were isolated for the hospital from Jan 2007 to Nov 2011.PCR method was used to analyze qacE△1-sul1genes in 36 strains of ESBLs-producing E.coli so as to study their prevalence.RESULTS Totally 1660 strains of ESBLs-producing E.coli were found with a positive rate of 45.0%.The drug resistance rates of the E.coli strains to amikacin,imipenem,meropenem,cefoxitin,levofloxacin,cefoperazone/sulbactam and piperacillin/tazobactam were relatively low,and the strains had produced certain drug resistance to other antibiotics.The result of the drug susceptibility testing of the 36 strains of ESBLs-producing E.coli indicated that the strains were fully resistant to ampicillin,cefazolin,cefuroxime,and gentamicin,and that no strains of imipenem-resistant or meropenem-resistant strains were detected;totally 22 strains were found positive for qacE△1-sul1 genes among the 36 strains of ESBLs-producing E.coli,with a positive rate of 61.1%.CONCLUSION The drug resistance of E.coli is severe,which is basically stable in the past several years.Furthermore,the ESBLs-producing E.coli strains show multi-drug resistance.The positive rate of the qacE△1-sul1 genes is high in the ESBLs-producing E.coli,which is closely related to its multi-drug resistance." @default.
- W2390816148 created "2016-06-24" @default.
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- W2390816148 date "2013-01-01" @default.
- W2390816148 modified "2023-09-26" @default.
- W2390816148 title "Study on drug resistance of Escherichia coliand the disinfectant-resistant genes" @default.
- W2390816148 hasPublicationYear "2013" @default.
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