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- W2390857198 abstract "Mycobacterium tuberculosis (M.tuberculosis)is an intracellular bacterial pathogen for which macrophages are the host cells.M.tuberculosis uses various mechanisms to evade immune surveillance and attacks by macrophages.M.tuberculosis survives and proliferates in macrophages by preventing fusion of lysosomes and reducing macrophage apoptosis and sensitivity of macrophage responses to stimulation.However,macrophages are the main antibacterial immune effector cells,and they exert their effects via immune modulation and antigen presentation by direct killing and secretion of several cytokines.Further study on the mechanisms of immune evasion by M.tuberculosis and the immunological role of macrophages in tuberculosis infection is important for insights into the anti-tuberculosis immune mechanisms in the host and design of new anti-tuberculosis vaccines." @default.
- W2390857198 created "2016-06-24" @default.
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- W2390857198 date "2010-01-01" @default.
- W2390857198 modified "2023-09-23" @default.
- W2390857198 title "Interactions between Mycobacterium tuberculosis and macrophages" @default.
- W2390857198 hasPublicationYear "2010" @default.
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