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- W2390900658 abstract "Objective: To observe the effect of Kangxian Yixin prescription on expression of Angiotensin Ⅱ(Ang Ⅱ) in rats with dilated cardiomyopathy(DCM).Methods: Wistar rats were fed furazolidone to establish dilated cardiomyopathy model,then were randomly grouped and with drug intervention for 8 weeks,immunohistochemical staining of the myocardial expression of Ang Ⅱ.Results: The comparison of the expression of Ang Ⅱ: the high dosage and captopril group,the high dosage group and the captopril group compared with the model group were significantly lower for Ang Ⅱ expression,detected by immunohistochemistry of the three model group,the average optical density(AOD) were compared:(0.1820 ± 0.0235),(0.1827 ± 0.0180)、(0.1833 ± 0.0189) and(0.2324 ± 0.0408),all P0.05.Conclusion: Kangxian Yixin Prescription can reduce the AngⅡ in myocardium of DCM rats,which may be one of the interferencemechanisms of ventricular remodeling with DCM." @default.
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- W2390900658 date "2011-01-01" @default.
- W2390900658 modified "2023-09-23" @default.
- W2390900658 title "Effect of Kangxian Yixin prescription on AngII expression in rats with dilated cardiomyopathy" @default.
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