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- W2390903096 abstract "Objective To study the microvascular changes in the early stage of adult dermatomyositis. Method Two adult patients with dermatomyositis were studied in the early stage of the disease clinically and myopathologically. Results Both cases showed typical clinical symptoms with serological and electromyographical features for dermatomyositis. Muscle biopsies showed intramuscular vessels with intensive staining of non specific esterase, but minimal fiber necrosis and atrophy. Electron microscopy revealed necrosis and regeneration of capillary in which numerous microtubular inclusions appeared in their endothelial cells. Conclusions Our study demonstrated that microvasculopathy was an earlier pathological change than inflammatory infiltration and perifascicular atrophy in adult dermatomyositis. A microvasculopathy should be considered in diagnostic criteria of dermatomyositis, especially in the early or mild cases." @default.
- W2390903096 created "2016-06-24" @default.
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- W2390903096 date "2000-01-01" @default.
- W2390903096 modified "2023-09-25" @default.
- W2390903096 title "An early pathological changes for adult dermatomyositis" @default.
- W2390903096 hasPublicationYear "2000" @default.
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