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- W2390916848 abstract "The influences of twelve amino acids on S-adenosyl-L-methionine(SAM) production by Saccharomyces cerevisiae were investigated.The results showed that L-cystine,L-cysteine,L-lysine,L-histidine and L-methionine enhanced the production of SAM.Among them,L-lysine and L-histidine increased the biomass,thus increas the production of SAM.The others three promoted the concentration of SAM but had negative effects on biomass.Three different feeding methods were studied.It was found that L-lysine and L-histidine should be added in the cultural media,and the other should be fed during the first 24.The amounts of the five aminu avids were 1 g/L,1 g/L,1.5 g/L,1 g/L and 1 g/L respectively according to orthogonal optimization.Experiment on 5 L fermenter revealed that the accumulation of SAM reached 5.53 g/L,and 128 g/L of biomass was obtained." @default.
- W2390916848 created "2016-06-24" @default.
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- W2390916848 date "2007-01-01" @default.
- W2390916848 modified "2023-09-22" @default.
- W2390916848 title "Influences of amino acids on high-cell-density fermentation for S-adenosyl-L-methionine production" @default.
- W2390916848 hasPublicationYear "2007" @default.
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