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- W2390930669 abstract "Objective:To investigate the protective effect of leonurine(Leo) on pituitrin(Pit)-induced acute myocardial ischemia injury in rats.Methods:Pit was administrated intraperitoneally to induce acute myocardial ischemia injury in rats.The locomotion of J point(mv) and T wave(mv) in ECG was allowed to evaluate the degree of myocardial ischemia.The content of cardiac troponin T(cTnT) in serum and myocardium was measured by radio immunoassay.Results:In Leo(3,5,7,9 mg/kg) groups,the elevation of J point and T wave was lowered.The contents of cTnT in serum and myocardium were obviously decreased.Linear regression analysis(scatterplot) indicated that there is dose-effect relationship within certain dose range.Conclusions:Leo can inhibit Pit-induced myocardial ischemia injury,with dose-dependent effect." @default.
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- W2390930669 date "2007-01-01" @default.
- W2390930669 modified "2023-09-25" @default.
- W2390930669 title "Protective Effect of Leonurine on Acute Myocardial Ischemia Injury in Rats" @default.
- W2390930669 hasPublicationYear "2007" @default.
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