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- W2390933852 abstract "To investigate the movement of hypertensive cardiac hypertrophy and inters-titial myocardial collagen network remodeling and left ventricular function of rats.Methods: running training methods and abdominal aorta constriction separately established rat models of exercise-induced myocardial hypertrophy and hypertensive cardiac hypertrophy in rats.Isolated perfused heart of left ventricular function;scanning electron microscopy and transmission electron microscopy and image processing myocardial collagen network remodeling;of myocardial collagen by hydroxyproline concentration;Western-blot for type Ⅰ,Ⅲ collagen analysis.Results: The mean arterial blood pressure of hypertensive rats(P0.05) is always higher,while the training group(P0.05) in arterial blood pressure is always low;hypertensive rats than diastolic velocity training group(P0.05);hypertensive rats with left ventricular hydroxyproline concentration was significantly higher(P0.05),while the training and left ventricular hydroxyproline concentration did not significantly incr-ease;hypertensive rat left ventricle III collagen and the ratio of type I collagendecreased significantly(P0.05),while the training group did not show the same results.Conclusion: Exercise training can make the myocardial cells and simultaneous increase collagen,improve cardiac function,myocardial systolic and diastolic performance enhancement;and chronic hypertension leads to myocardial cells in rats with a disproportionate growth of collagen,interstitial collagen over-hyperplasia,cardiac damage.Collagen network remodeling of rat left ventricular function has important implications." @default.
- W2390933852 created "2016-06-24" @default.
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- W2390933852 date "2013-01-01" @default.
- W2390933852 modified "2023-09-23" @default.
- W2390933852 title "Effects of Exercises and Hypertensive Cardiac Hypertrophy on Collagen Network Remodeling and Left Ventricular Function" @default.
- W2390933852 hasPublicationYear "2013" @default.
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