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- W2390947074 abstract "Objective To investigate the significance of expression of intracellular adhesion molecules 1 (ICAM 1) on Henoch Schoenlein purpura,one of the systemic vasculitis.Methods Thirteen children with Henoch Schoenlein purpura and 5 healthy children as the control were enrolled in this study.ICAM 1 in their blood was detected by semi quantity reverse transcription polymerase chain reaction (RT PCR).Results ICAM 1 in 12 sick children were positive (92 31%),and 4 healthy were negative transcripted.Six of 13 sick children suffered from renal damage (46 15%),in which ICAM 1 in 5 cases was positive.The rank tesk result between the two groups′PCR products in amount revealed that there was a significant difference ( P 0 005).Conclusion ICAM 1 is one of the markers of systemic and vascular inflammation and endothelial damage.The positive expression of ICAM 1 suggests that the purpura may be in active phase,and ICAM 1 in the active phase of purpura nephritis could be obviously increased." @default.
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- W2390947074 date "1999-01-01" @default.
- W2390947074 modified "2023-09-23" @default.
- W2390947074 title "Significance of expression of ICAM 1 in blood on Henoch Schoenlein purpura" @default.
- W2390947074 hasPublicationYear "1999" @default.
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