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- W2390958478 abstract "Objective To explore the mechanism of myocardial injury by T 2 toxin with selenium-deficiency and the relationship of Keshan disease.Methods Using rats as animal model of selenium deficiency diet and T 2 toxin attack. The glutathione peroxidase (GSH Px) and apoptosis of the myocardial tissue by biochemistry and TUNEL were observed and the level of selenium and GSH Px were compared with different rat groups.Results The damage of rat heart were found both in T 2 toxion with selenium defficiency group and T 2 toxin without selenium defficiency group; The lowest level of GSH Px activity and most numbers of apoptosis cell were found in T 2 toxion with selenium defficiency group. Conclusions T 2 toxin with selenium defficiency can make rat heart damage easily;Lipid peroxidation and apoptosis involved in injury mechanism of myocardial damage. It can give a trail for study the etiology of Keshan disease." @default.
- W2390958478 created "2016-06-24" @default.
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- W2390958478 date "2001-01-01" @default.
- W2390958478 modified "2023-09-25" @default.
- W2390958478 title "Experimental study of myocardial injury induced by T-2 toxin" @default.
- W2390958478 hasPublicationYear "2001" @default.
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