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- W2390963439 abstract "Objective To investigate etiological factors of infection in patients in various stages of post-renal transplantation.Methods Retrospective analysis was made in 41 cases of infected patients who received kidney transplant between Jan. 2003 and Dec. 2004. The rate, location and etiological factors of the infection were analyzed.Results Infections developed in 41 of 69 patients (59.4 %) following renal transplantation. Infections occurred in various stages of post-transplantation, 11 of 41 cases (26.8%) in the first 30 days, 12 cases (29.3%) from the 30th day to the 90th, 7 cases (17.1%) from the 90th day to the 180th day, and 11 cases (26.8%) were after the 180th day. Concerning the location of the infection, 23 of 41 cases (56.1%) were pulmonary infections, 1 case (2.4%) pneumonia complicated with meningitis, 1 case (2.4%) pneumonia complicated with intestinal infection, 5 cases (12.2%) urinary infections, 2 (4.9%) incision infections, 1 (2.4%) nervous system infection, 1 (2.4%) abdominal cavity infection, and 7 cases (17.1%) with virus infection showed unclearly infected region. Pathogen was detected in 30 of 41 infected patients including bacteria in 10 cases, virus in 9 cases and mixed infections in 11 cases. In all infections, the numbers of isolates of Pseudomonas aeruginosa, Staphylococcus epidermidis and D group nonenterococcus from infected patients were at primacy, followed by malt Pseudomonas, Bacillus coli, Enterococcus faecium, immobile bacillus, sewer enteric bacilli, yellow bacilli, and D group enterococcus. In viral infections, the numbers of isolates of CMV and Adv3 were at primacy, followed by EB virus, Adv11, HSV1, HSV2, Cox virus, rubella virus, and Adv7 virus; in bacterial infections, the numbers of isolates of Pseudomonas aeruginosa, malt Pseudomonas and Bacillus coli were at primacy. After treatment, 34 cases recovered, 7 cases died, mortality rate was 17%. All the dead cases were pulmonary infection except one abdominal cavity infection. In dead cases, APACHE II grade was from 19 to 24 (22.57 ± 3.05), death risk index was from 19.26 to 44.23 (28.24 ± 8.89).Conclusion Infections after renal transplantation develop in various regions, pulmonary infection is most frequent. Empiric treatment based on the etiological findings of infected patient in various stages of post-renal transplantation may be useful. Prognosis can be assessed according to the APACHE II grade and death risk index." @default.
- W2390963439 created "2016-06-24" @default.
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- W2390963439 date "2006-01-01" @default.
- W2390963439 modified "2023-09-24" @default.
- W2390963439 title "Characteristics of the infection in various stages of post-renal transplantation." @default.
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