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- W2390988144 abstract "Objective To observe the effect of premarin and medroxyprogesterone acetate(MPA) on patients with osteoporosis of peirmenopausal period. Methods 46 subjects were randomly divided into the test and control group(both n=23).The control group were given amino acid calcium tablet,as well as MPA,for 6 months.Based on this,patients in the test group were sequentially administrated with premarin.The bone mineral density(BMD) and the other indexes related to bone metabolism were detected before and after treatment.Moreover,the adverse reactions were also observed. Results There was no difference in BMD,estradiol(E2),luteinizing hormone(LH),alkaline phosphatase(ALP) and urine calcium/creatinine(UCa/Cr) between the two groups.The above-mentioned 5 indexes were all significantly improved after treatment(p0.05) for both groups.But compared with the control group,BMD in the test group was significantly higher,and the ALP and UCa/Cr were lower(both p0.05).For the clinical outcome and adverse reaction ratios,there was no difference between the two groups after treatment either. Conclusion Compared with MPA,premarin could better improve bone metabolism and thus treat patients with osteoporosis of peirmenopausal period more effectively." @default.
- W2390988144 created "2016-06-24" @default.
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- W2390988144 date "2011-01-01" @default.
- W2390988144 modified "2023-09-24" @default.
- W2390988144 title "EFFECT OF PREMARIN AND MEDROXYPROGESTERONE ACETATE(MPA) ON PATIENTS WITH OSTEOPOROSIS OF PEIRMENOPAUSAL PERIOD" @default.
- W2390988144 hasPublicationYear "2011" @default.
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