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- W2391014722 abstract "ObjectiveTo study the cytotoxic effects of ShuGanShuRu Granules(SGSR)on MCF-7 human breast cancer cells in vitro.MethodsBy using modified MTT assay,the influences of SGSR upon the OD values of MTT were studied and the cytotoxicity of SGSR on MCF-7 human breast cancer cell were monitored.ResultsThe OD values of the different concentrations of SGSR were all lower than that of controlled group,which indicated that all concentrations of SGSR have cytotoxic effects on MCF-7 cells,especially the killing rate of groups of 4,l,0.25g/ ml reached 99.9%,99% and 95.55% respectively.There were statistically striking differences(P0.01) and showed good dosage-effect relation.The killer rate is considerably higher than that of β-Carotine(β-CA) and β-CA added SGSR groups.ConclusionThis study reveals that SGSR has obvious cytotoxic effects on MCF-7 cells.Its mechanism might be associated with the anti-mutation effects as well as the direct killing activities,thus making DNA chains broken resulting in the death of tumor cells." @default.
- W2391014722 created "2016-06-24" @default.
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- W2391014722 date "2006-01-01" @default.
- W2391014722 modified "2023-09-25" @default.
- W2391014722 title "The Cytotoxic Effects of ShuGanShuRu Granules on MCF-7 Human Breast Cancer Cells in vitro" @default.
- W2391014722 hasPublicationYear "2006" @default.
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