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- W2391098910 abstract "Objective By comparing the changes of NSE protein expression in hippocampus of epilepsy rats induced by kainic acid (KA) after intervened by topirate and baclofen to explore the effect of topirate and baclofen on brain injury and neural protection in induced epilepsy rats. Methods Under three-dimensional orientator, kainic acid was injected into amygdaloid nucleus of rats to prepare epilepsy rats model. These rats were randomly divided into normal group, KA group, topiramate group and baclofen group, the expression of NSE was determined by immunohistochemistry methods. Results Comparing to that in control group, the NSE expression in KA group significantly decreased. The NSE expression in topiramate and baclofen group increased comparing to that in KA group (P0.05).Conclusions NSE protein expression in epilepsy rats decreased induced by KA and upregulated induced by topirate and baclofen." @default.
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- W2391098910 date "2005-01-01" @default.
- W2391098910 modified "2023-09-25" @default.
- W2391098910 title "The changes of NSE protein expression in hippocampus of epilepsy rats induced by kainic acid after intervened by topirate and baclofen" @default.
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