Matches in SemOpenAlex for { <https://semopenalex.org/work/W2391125540> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2391125540 abstract "Objective To study the effect of BCL-2 γ-radiation on BCL-2 gene in dogs, and its relationship and signifcane on apoptosis of proliferated smooth muscle cells of bile duct wall. Methods The ~(103)Pd (radioactivity) stent(experiment group) or ordinary stent(control group) was positioned into the target segment of bile duct. The injured bile duct segments were dissected free from the dogs, and BCL-2 gene in the (control) and r-radiation-induced apoptotic smooth mucle cells of bile duct wall was analysed by using (immuno-histochemical) technique. The number of apoptotic cells was counted, and size of lumen of bile duct in both groups was measured by a computerized imaging system.Results BCL-2 gene expression was weaker in the ~(103)Pd radioactive stent group than in the ordinary stent group. The group of dogs with low expression of BCL-2 genes showed marked apoptosis of proliferated smooth mucle cells of bile duct and there was no overt stenosis of extrahepatic bile ducts. The group that showed high expression of BCL-2 gene did not show marked apoptosisi of proliferated smooth muscle cells of bile duct, and there was marked stenosis of extrahepatic bile duct.Conclusions The expression level of BCL-2 in experimental dogs is related to the develoment of (cellular) apoptosis and to radiation sensitivity of the cells. ~(103)Pd radioactive stent can reduce the expression of BCL-2 gene, promote apoptosis of proliferated smooth muscle cells of bile duct, and suppress stricture (formation) of extrahepatic bile duct." @default.
- W2391125540 created "2016-06-24" @default.
- W2391125540 creator A5056037038 @default.
- W2391125540 date "2005-01-01" @default.
- W2391125540 modified "2023-09-25" @default.
- W2391125540 title "The effect of intracholangeal radiation on the expression of BCL-2 in dogs and its relationship to apoptosis of smooth muscle cells" @default.
- W2391125540 hasPublicationYear "2005" @default.
- W2391125540 type Work @default.
- W2391125540 sameAs 2391125540 @default.
- W2391125540 citedByCount "0" @default.
- W2391125540 crossrefType "journal-article" @default.
- W2391125540 hasAuthorship W2391125540A5056037038 @default.
- W2391125540 hasConcept C126322002 @default.
- W2391125540 hasConcept C131631996 @default.
- W2391125540 hasConcept C142724271 @default.
- W2391125540 hasConcept C190283241 @default.
- W2391125540 hasConcept C2775955815 @default.
- W2391125540 hasConcept C2778583881 @default.
- W2391125540 hasConcept C2779777945 @default.
- W2391125540 hasConcept C2781212128 @default.
- W2391125540 hasConcept C2992686903 @default.
- W2391125540 hasConcept C55493867 @default.
- W2391125540 hasConcept C71924100 @default.
- W2391125540 hasConcept C86803240 @default.
- W2391125540 hasConceptScore W2391125540C126322002 @default.
- W2391125540 hasConceptScore W2391125540C131631996 @default.
- W2391125540 hasConceptScore W2391125540C142724271 @default.
- W2391125540 hasConceptScore W2391125540C190283241 @default.
- W2391125540 hasConceptScore W2391125540C2775955815 @default.
- W2391125540 hasConceptScore W2391125540C2778583881 @default.
- W2391125540 hasConceptScore W2391125540C2779777945 @default.
- W2391125540 hasConceptScore W2391125540C2781212128 @default.
- W2391125540 hasConceptScore W2391125540C2992686903 @default.
- W2391125540 hasConceptScore W2391125540C55493867 @default.
- W2391125540 hasConceptScore W2391125540C71924100 @default.
- W2391125540 hasConceptScore W2391125540C86803240 @default.
- W2391125540 hasLocation W23911255401 @default.
- W2391125540 hasOpenAccess W2391125540 @default.
- W2391125540 hasPrimaryLocation W23911255401 @default.
- W2391125540 hasRelatedWork W2347676543 @default.
- W2391125540 hasRelatedWork W2348850601 @default.
- W2391125540 hasRelatedWork W2349239525 @default.
- W2391125540 hasRelatedWork W2352945697 @default.
- W2391125540 hasRelatedWork W2353544209 @default.
- W2391125540 hasRelatedWork W2355722223 @default.
- W2391125540 hasRelatedWork W2358190962 @default.
- W2391125540 hasRelatedWork W2358496119 @default.
- W2391125540 hasRelatedWork W2362860379 @default.
- W2391125540 hasRelatedWork W2365254762 @default.
- W2391125540 hasRelatedWork W2365783464 @default.
- W2391125540 hasRelatedWork W2366453347 @default.
- W2391125540 hasRelatedWork W2375125837 @default.
- W2391125540 hasRelatedWork W2377475897 @default.
- W2391125540 hasRelatedWork W2386276528 @default.
- W2391125540 hasRelatedWork W2388438391 @default.
- W2391125540 hasRelatedWork W2389261479 @default.
- W2391125540 hasRelatedWork W2393617350 @default.
- W2391125540 hasRelatedWork W2396943440 @default.
- W2391125540 hasRelatedWork W3031157194 @default.
- W2391125540 isParatext "false" @default.
- W2391125540 isRetracted "false" @default.
- W2391125540 magId "2391125540" @default.
- W2391125540 workType "article" @default.