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- W2391139441 abstract "Objective To investigate the effect of Ginkgo biloba extract (GBE) on the pathology change of cerebral tissue in rat focal cerebral ischemia under different cerebral temperature.Methods Determined at different brain temperature,24 wistar rats were randomly divided into 6 groups,including the sham operated group in normal temperature,cerebral ischemia group in normal temperature,cerebral ischemia group in subhypothermia,GBE group in mild hypothermia temperature,GBE group in normal temperature,GBE group under subhypothermia temperature.The model of rat middle cerebral artery ischemia reperfusion was established as re-perfusion four hours after two hours ischemia.The light microscope and electron microscopy were used to observe the pathology change of cerebral tissue in rat focal cerebral ischemia under different cerebral temperature.Results The pathological damage rang and extent of cerebral tissue were becoming more seriousier in GBE group under subhypothermia temperature,cerebral ischemia group in subhypothermia,GBE group in normal temperature,cerebral ischemia group in normal temperature,GBE group in mild hypothermia temperature respectively.Conclusion During the processes of cerebral ischemic,different brain temperature may affect the of.This GBE′s neuroprotective(37.0~37.5)℃ effect was limited under normal temperature,and was enhanced under subhypothermia(32.0~32.5)℃.It suggests that the enhanced neuroprotection in focal cerebral ischemia tissue of GBE group under subhypothermia isn′t the result of either subhypothermia or GBE intervention factor,but the main effect of subhypothermia and cooperation of both." @default.
- W2391139441 created "2016-06-24" @default.
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- W2391139441 date "2010-01-01" @default.
- W2391139441 modified "2023-09-24" @default.
- W2391139441 title "The Effects of Ginkgo Biloba Extract under Different Cerebral Temperature on the Pathology Change of Cerebral Tissue in Rat Focal Cerebral Ischemia" @default.
- W2391139441 hasPublicationYear "2010" @default.
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