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- W2391158501 abstract "Objective To compare the immune protective effect of three antigens of Trichinella spiralis adult worm in mice. Methods Intestinal adult worms and muscle larvae of T. spiralis in mice of each group were examined on day 7 and day 30 postchal-lenge respectively. Moreover, the level of serum IgG to muscle larvae antigen of T. spiralis was detected by ELISA on day 30 postchallenge. Blood absolute eosinophil(EOS) number was counted on day 7 and day 30 postchallenge. Results Intestinal adult worm reduction rates were 84. 48% , 89. 98% , 85. 16% in adult worm somatic antigen, adult worm excretory-secretory antigen and adult worm surface antigen groups respectively. Muscle larvae reduced were 69. 82% , 78. 80% , 73. 94% respectively. The antibody titer in all immunized groups increased significantly, the GMRT values in three immunized groups were 6. 96, 7. 99, 6. 06 times as high as unimmunized group respectively. Periphery blood EOS enhanced since day 7 postchallenge and day 30 postchallenge, were significantly higher than that of unimmunized group. Conclusion T. spiralis adult worm antigen can induce strong resistance of host to a subsequent challenge infection and activate specific humoral and cellular immunity. Among these antigens, excretory-secretory antigen is more immunogenic." @default.
- W2391158501 created "2016-06-24" @default.
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- W2391158501 date "2004-01-01" @default.
- W2391158501 modified "2023-09-24" @default.
- W2391158501 title "STUDY ON THE IMMUNE PROTECTIVE EFFECT OF TRICHINELLA SPIRALIS ADULT WORM ANTIGENS" @default.
- W2391158501 hasPublicationYear "2004" @default.
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