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- W2391174226 abstract "Objective To analyze the clinical and pathological features of sarcoidosis with renal involvement and its treatment.Methods The clinical and pathological features and therapeutic result of two female patients of sarcoidosis with renal involvement were analyzed retrospectively.The related literature was reviewed,and the experiences in diagnosis and treatment of sarcoidosis with renal involvement were summarized.Results Both sarcoidosis patients with renal involvement showed high serum creatinine.Case 1 suffered from localized renal sarcoidosis,and renal biopsy showed granulomatous interstitial nephritis.Case 2 suffered from typical sarcoidosis,the extrarenal involvements included pathological changes in lung,eye,lymph nodes and parotid gland,and with hypercalcaemia and renal calculus.Renal biopsy showed granulomatous interstitial nephritis and calcareous deposition in renal tissue.The duration from onset of initial symptoms to final diagnosis of the two cases was 1 year and 5 years,respectively.The urinary protein level and high serum creatinine in the two cases decreased to normal range after one-month of treatment with steroids and immunosuppressant,and the hypercalcaemia in case 2 came down to normal range.Conclusions The diagnosis of sarcoidosis is often delayed and missed.The patient with sarcoidosis of renal tubule involvement should undergo renal biopsy immediately,and be treated with steroids and immunosuppressant after diagnosis is established." @default.
- W2391174226 created "2016-06-24" @default.
- W2391174226 creator A5058928208 @default.
- W2391174226 date "2010-01-01" @default.
- W2391174226 modified "2023-09-23" @default.
- W2391174226 title "Sarcoidosis with renal involvement:two cases report and review of literature" @default.
- W2391174226 hasPublicationYear "2010" @default.
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