Matches in SemOpenAlex for { <https://semopenalex.org/work/W2391176177> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2391176177 abstract "AIM: To investigate the suppressive effects of dehydroepiandrosterone(DHEA) and glucose-6-phosphate dehydrogenase(G6PD) antisense oligodeoxynucleotides on Raji cells.METHODS: Raji cell line was cultured in vitro in the presence of DHEA at different concentrations ranged from 0.05 μmol/L to 500 μmol/L or G6PD antisense oligodeoxynucleotides.The viability and proliferation of the cells pretreated with dehydroepiandrosterone or G6PD antisense oligodeoxynucleotides were evaluated.Meanwhile,intracellular activities and mRNA expression of G6PD were analyzed.RESULTS: DHEA and G6PD antisense oligodeoxynucleotides does not influence the viability of cells in culture.Raji cells treated with DHEA at concentration of 50 μmol/L or 500 μmol/L for 72 h or with 10.0 μmol/L G6PD antisense oligodeoxynucleotides for 48 h had significant lower cell numbers compared with control(P0.01).Raji cells treated with DHEA at concentration more than 5.0 μmol/L for 72 h had significant decreased G6PD activities(P0.01) but no change in mRNA expression levels was observed.With 10.0 μmol/L G6PD antisense oligodeoxynucleotides pretreatment for 48 h,the G6PD mRNA expression levels and activities were significantly decreased(P0.01).CONCLUSION: DHEA or G6PD antisense oligodeoxynucleotides at specific concentration have suppressive effects on G6PD activities and proliferation in Raji cells to a certain extent,but the suppressive mechanisms are different." @default.
- W2391176177 created "2016-06-24" @default.
- W2391176177 creator A5019081631 @default.
- W2391176177 date "2006-01-01" @default.
- W2391176177 modified "2023-09-25" @default.
- W2391176177 title "Effects of DHEA and G6PD antisense oligodeoxynucleotides on Raji cells" @default.
- W2391176177 hasPublicationYear "2006" @default.
- W2391176177 type Work @default.
- W2391176177 sameAs 2391176177 @default.
- W2391176177 citedByCount "0" @default.
- W2391176177 crossrefType "journal-article" @default.
- W2391176177 hasAuthorship W2391176177A5019081631 @default.
- W2391176177 hasConcept C104317684 @default.
- W2391176177 hasConcept C105580179 @default.
- W2391176177 hasConcept C153911025 @default.
- W2391176177 hasConcept C16232356 @default.
- W2391176177 hasConcept C185592680 @default.
- W2391176177 hasConcept C202416437 @default.
- W2391176177 hasConcept C202751555 @default.
- W2391176177 hasConcept C2776992908 @default.
- W2391176177 hasConcept C2777911890 @default.
- W2391176177 hasConcept C53227056 @default.
- W2391176177 hasConcept C54355233 @default.
- W2391176177 hasConcept C55493867 @default.
- W2391176177 hasConcept C71315377 @default.
- W2391176177 hasConcept C79879829 @default.
- W2391176177 hasConcept C81885089 @default.
- W2391176177 hasConcept C86803240 @default.
- W2391176177 hasConceptScore W2391176177C104317684 @default.
- W2391176177 hasConceptScore W2391176177C105580179 @default.
- W2391176177 hasConceptScore W2391176177C153911025 @default.
- W2391176177 hasConceptScore W2391176177C16232356 @default.
- W2391176177 hasConceptScore W2391176177C185592680 @default.
- W2391176177 hasConceptScore W2391176177C202416437 @default.
- W2391176177 hasConceptScore W2391176177C202751555 @default.
- W2391176177 hasConceptScore W2391176177C2776992908 @default.
- W2391176177 hasConceptScore W2391176177C2777911890 @default.
- W2391176177 hasConceptScore W2391176177C53227056 @default.
- W2391176177 hasConceptScore W2391176177C54355233 @default.
- W2391176177 hasConceptScore W2391176177C55493867 @default.
- W2391176177 hasConceptScore W2391176177C71315377 @default.
- W2391176177 hasConceptScore W2391176177C79879829 @default.
- W2391176177 hasConceptScore W2391176177C81885089 @default.
- W2391176177 hasConceptScore W2391176177C86803240 @default.
- W2391176177 hasLocation W23911761771 @default.
- W2391176177 hasOpenAccess W2391176177 @default.
- W2391176177 hasPrimaryLocation W23911761771 @default.
- W2391176177 hasRelatedWork W1990806563 @default.
- W2391176177 hasRelatedWork W2032676984 @default.
- W2391176177 hasRelatedWork W2051903497 @default.
- W2391176177 hasRelatedWork W2070456887 @default.
- W2391176177 hasRelatedWork W2084947298 @default.
- W2391176177 hasRelatedWork W2127421427 @default.
- W2391176177 hasRelatedWork W2350899351 @default.
- W2391176177 hasRelatedWork W2355631962 @default.
- W2391176177 hasRelatedWork W2361588901 @default.
- W2391176177 hasRelatedWork W2364956244 @default.
- W2391176177 hasRelatedWork W2370983733 @default.
- W2391176177 hasRelatedWork W2373481295 @default.
- W2391176177 hasRelatedWork W2378723642 @default.
- W2391176177 hasRelatedWork W2380947081 @default.
- W2391176177 hasRelatedWork W2384122010 @default.
- W2391176177 hasRelatedWork W2436541701 @default.
- W2391176177 hasRelatedWork W3028812309 @default.
- W2391176177 hasRelatedWork W3029022614 @default.
- W2391176177 hasRelatedWork W3031082992 @default.
- W2391176177 hasRelatedWork W3147440976 @default.
- W2391176177 isParatext "false" @default.
- W2391176177 isRetracted "false" @default.
- W2391176177 magId "2391176177" @default.
- W2391176177 workType "article" @default.