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- W2391196146 abstract "Objective To investigate the value of 3. 0T DWI in the differential diagnosis of central gland prostate cancer( CGPCa) and benign prostatic hyperplasia( BPH). Methods The MRI and DWI imaging dates of 34 cases of CGPCa( positive group) and 70 cases of BPH( negative group) were analyzed retrospectively. MR characteristics of T2WI,DWI and ADC values were compared in two groups. ROC cure was used to determine the cutoff value for the CGPCa detected with the ADC value. Sensitivity and specificity were calculated. Results The mean ADC value of CGPCa group was( 0. 78 ±0. 15) × 10- 3mm2/ s. The mean ADC value of glandular BPH,stromal BPH and mixture BPH were( 1. 49 ± 0. 11) × 10- 3mm2/ s,( 1. 12 ± 0. 14) × 10- 3mm2/ s and( 1. 34 ± 0. 14) × 10- 3mm2/ s respectively. The mean ADC value of three type of BPH was( 1. 28 ± 0. 20) × 10- 3mm2/ s. The mean ADC value had statistically significant difference between two groups( t= 13. 77,P 0. 01). According to the ROC analysis,when the cutoff value was 1. 05 × 10- 3mm2/ s,the maximal Youden's index were 0. 80,the diagnostic sensitivity,specificity and accuracy was 82. 90% 、97. 10% and 94. 32% respectively. The mean ADC value of the low risk group( Gleason score 7) and the intermediate and high risk group( Gleason score ≥7)were( 0. 89 ± 0. 26) × × 10- 3mm2/ s and( 0. 74 ± 0. 13) × 10- 3mm2/ s,respectively( t = 3. 09,P 0. 01). Conclusion DWI is helpful to differential diagnosis of CGPCa and BPH." @default.
- W2391196146 created "2016-06-24" @default.
- W2391196146 creator A5034708125 @default.
- W2391196146 date "2013-01-01" @default.
- W2391196146 modified "2023-09-24" @default.
- W2391196146 title "Value of 3. 0 T MR Diffusion-Weighted Imaging in Differential Diagnosis of Prostatic Central Gland Cancer and Benign Prostatic Hyperplasia" @default.
- W2391196146 hasPublicationYear "2013" @default.
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