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- W2391216615 abstract "Objective To study the apo-E gene polymorphisms and the lipoprotein level character of different gene expression in patients with cerebrovascular infarction(CI) and intracerebral hemorrhage(ICH).Methord With case-control study method,the apo-E gene expression,its allele frequency and the levels of serum lipids in patients with cerebrovascular infarction or with intracerebral hemorrhage and the control were compared.Result The CI group had a higher apo-E e4 allele frequency(10%) than controls(4.6%)(P0.05).The levels of TC and LDL-c were higher,and HDL-c was lower in CI group with e2 and e4 allele than that in ICH group.But the level of TG in CI group with e4 allele was significant higher than that in controls(P0.05).Conclusion Apo-E e4 allele is a genetic susceptible factor for CI.The gene polymorphism of apo-E wasn't associated with ICH.Apo-E could increase the risk of CI through influencing the metabolism of serum lipids." @default.
- W2391216615 created "2016-06-24" @default.
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- W2391216615 date "2006-01-01" @default.
- W2391216615 modified "2023-09-26" @default.
- W2391216615 title "The Study on Apolipoprotein E Gene Polymorphism Characteristics of Cerebral Infarction and Intracerebral Hemorrhage" @default.
- W2391216615 hasPublicationYear "2006" @default.
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