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- W2391221626 abstract "Objective To study how to improve the methods of myocardial infarction modelling in rats with a low mortality.Methods 330 Adult male Sprague-Dawley rats underwent the left descending coronary artery ligation,then being divided randomly into 3 sub-groups according to the course:1-week,2-week,4-week sub-groups.Eight rats underwent sham operation,being killed after 4w.Some details affecting the mortality of the rats model,such as anaesthesia,artificial respiration,thoracotomy and ligating the left descending coronary artery were studied.Results The mortality of the rat models was decreased from 49%to 27%in 2-week sub-group after some methods was improved.Conclusion Lung injury is the most important factor.The correct applying of anaesthetic and the careful objection after operation are important factors affecting the mortality of the rat models." @default.
- W2391221626 created "2016-06-24" @default.
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- W2391221626 date "2009-01-01" @default.
- W2391221626 modified "2023-09-25" @default.
- W2391221626 title "Discussion of some methods of myocardial infarction modelling in rats" @default.
- W2391221626 hasPublicationYear "2009" @default.
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