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- W2391223377 abstract "Objective:To investigate the clinical efficacy and impact of Qingnao Jiangya tablets(QJT) on endothelial function in the treatment of liver yang hypertension.Method: One hundred and fifty-six patients with hypertension were randomly divided into treatment group of 79 cases and control group of 77 cases.Grade Ⅰ hypertension was treated with QJT;Grade Ⅱ hypertension was additionally treated by QJT based on the original treatment,The controls were only received placebo.QJT was orally given 4-6 tablets tid for 4 weeks.Blood pressure,liver yang score,nitric oxide(NO) and endothelin(ET-1) were evaluated for the two groups.Result: QJT significantly reduced systolic blood pressure(SBP) and diastolic blood pressure(DBP) for the grade Ⅰ and grade II hypertension patients(P0.01).QJT significantly improved the patient's liver yang scores,and the disease efficiency and syndromes efficiencies were 84.81%,89.87%(P0.01).QJT increased NO level,reduced ET-1 level and adjusted NO/ET-1 ratio(P0.01).Conclusion: QJT had obvious antihypertensive effect for grade Ⅰ and grade Ⅱ hypertensive patients.It could improve clinical symptoms,and its mechanism may be achieved by adjusting the ratio of NO/ET-1." @default.
- W2391223377 created "2016-06-24" @default.
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- W2391223377 date "2012-01-01" @default.
- W2391223377 modified "2023-09-23" @default.
- W2391223377 title "Clinical Efficacy and Impact of Qingnao Jiangya Tablets on Endothelial Function in Treatment of Liver Yang Hypertension" @default.
- W2391223377 hasPublicationYear "2012" @default.
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