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- W2391265870 abstract "Objetivce:To evaluate the relation between Down's syndrome and the ductus venous(DV) velosity waveform in early second trimester and the second trimester genetic sonogram.Methods:239 cases of pregnant women enrolled and plan to delivery in obstetric and gynecology hospital of Fudan university were received the ultrasonic examination including DV velosity waveform in early second trimester and genetic ultrasonic screening during second trimester by Voluson 730 ultrasonic machine of GE company.Fetal chromesome examination via amnion puncture was adviced when any abnormality was found.All women were followed to delivery and the statistic methods were the Bayes canonical discriminant function and variance analysis.Results:During the 239 cases of enrolled pregnant women,154 cases underwent the DV velosity waveform measurement in early second trimester and 157 cases had the ultrasonic screening test during second trimester.106 cases received the amnion puncture and chromesome analysis,2 cases of Down's were found.Among the 157 cases of ultrasonic screening examination during second trimester,different abnormalities were found,including 14 cases of nuchal thickening,6 cases of hyperechoic bowel,7 cases of choroid plexus cyst,5 cases of pyelectasis and 0ne case of fetal hydrops.The Bayes canonical discriminant function is as follows:The normal fetus:Y=0.705+1.024×echogenic intracardiac focus;the Down's fetus:Y=-54.538+43.691×echogenic intracardiac focus+128×fetal hydrops.No significant statistic differences were found in intraobserver variability of transdominal Doppler velocimetry measurements of the fetal DV via variance analysis,and there was no relation between DV and Down's in our research.Conclusion:The second trimester genetic sonogram is useful in detecting Down's fetus,and the Bayes canonical discriminant function will help the pregnant woman to decide whether to have the amnion puncture or not." @default.
- W2391265870 created "2016-06-24" @default.
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- W2391265870 date "2008-01-01" @default.
- W2391265870 modified "2023-09-23" @default.
- W2391265870 title "Down's syndrome:the value of ductus venous velosity waveform in early second trimester and the second trimester genetic sonogram" @default.
- W2391265870 hasPublicationYear "2008" @default.
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