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- W2391307513 abstract "Fluoro-L-DOPA was synthesized from the starting material 6-nitropiperonal via a multi-step reaction by the nucleophilic fluorination,reductive iodination,chiral catalytic phase-transfer alkylation,and hydrolysis reactions.The enantiomeric purity of 6-fluoro-L-DOPA was determined by the HPLC method using a chiral mobile phase and reversed-phase C 18 column.The overall chemical yield from 6-nitropiperonal was 38%,and the enantiomeric purity of 6-fluoro-L-DOPA was above 95%." @default.
- W2391307513 created "2016-06-24" @default.
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- W2391307513 date "2002-01-01" @default.
- W2391307513 modified "2023-09-27" @default.
- W2391307513 title "Nucleophilic enantioselective synthesis of 6-fluoro-L-DOPA via chiral catalytic phase-transfer alkylation" @default.
- W2391307513 hasPublicationYear "2002" @default.
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