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- W2391334223 abstract "Purpose To prepare bFGF-PLGA microspheres and to investigate the characteristics.Methods The bFGF-PLGA microspheres were prepared by W1/O/W2 multiple emulsion volatilizing method,the morphology was investigated using scanning electron microscope(SEM),the ELISA method was used to establish the regression equation and to detect the drug loading amount and encapsulation efficiency,as well as sustained-release profile in vitro.Results The microspheres seemed to be smooth and uniform with mean particle size of(0.75±0.08) μm,the the drug loading amount and encapsulation efficiency were [(59.9±1.9)×10-3]% and (79.9±2.8)%,respectively,the accumulative release ratio was up to 80% in the continuous period of forty-five days.Conclusion The bFGF-PLGA microspheres have better pharmaceutical properties and long-time sustained release effect in vitro." @default.
- W2391334223 created "2016-06-24" @default.
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- W2391334223 date "2010-01-01" @default.
- W2391334223 modified "2023-09-26" @default.
- W2391334223 title "Preparation of bFGF-PLGA controlled-release microspheres and their sustained release performance in vitro" @default.
- W2391334223 hasPublicationYear "2010" @default.
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