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- W2391346238 abstract "Objective Effects of recombinant human interferon α-1b(IFNa-1b) the joint pidotimod immune function in children with recurrent respiratory tract infections(RRTI).Methods Choose met the inclusion criteria,66 patients with recurrent respiratory tract infections in children,Were randomly divided into a treatment group of 33 patients and a control group of 33 patients.The treatment group was given the IFNa-1b intramuscular injection,once a day,once every five days While oral horse Duomo De every time a(400 mg),once daily,continuous medication for 60 days.Control group:conventional empirical ribavirin or Xiyanping anti-infective symptomatic treatment to ease the period of enhanced care to avoid the cold.At the same time the content detection of two groups of children with peripheral blood T lymphocyte subsets and the expression level of immunoglobulin.Results After treatment,CD3+,CD4+,the percentage of T cells were(57.02 ± 6.05)%,(48.26 ± 1.03)% and the ratio of CD4+ /CD8+(1.69 ± 0.15) was significantly higher than that in control group(P 0.01),CD8+(27.04 ± 3.91)% was significantly lower than that of the control group(P 0.01) had significant difference;The treatment group of immunoglobulin IgG,IgA and IgM levels were(8.39 ± 3.41) g/L,(8.75 ± 0.28) g/L and(1.64 ± 0.12) g/L,there was significant difference compared with the control group(P 0.01).Conclusion RRTI low immune function in children,recombinant human interferon alfa-1b United pidotimod can significantly improve(RRTI) children 's cellular and humoral immune function,effectively reduce the number of sick." @default.
- W2391346238 created "2016-06-24" @default.
- W2391346238 creator A5054979279 @default.
- W2391346238 date "2013-01-01" @default.
- W2391346238 modified "2023-09-25" @default.
- W2391346238 title "Recombinant human interferon α-1b Joint pidotimod impact on the immune status of children with recurrent respiratory infections" @default.
- W2391346238 hasPublicationYear "2013" @default.
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