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- W2391382012 abstract "Objective To investigate the high risk factors in the development of pereventricular leucomalacia(PVL) in preterm infants.Methods Sixty-nine premature infants admitted to our hospital's neonatal intensive care unit between January 2007 to June 2008 were studied.PVL were diagnosed with cystic formation on serial cranial sonography.Premature infants without cystic formation were kept as control group.Twenty-three perinatal factors were analyzed by Crosstabs Test or t Test with SPSS 13.0. Logistic regression analysis was used to identify the high risk factors associated with the development of PVL.Results Twenty-one cases were diagnosed as PVL group,48 cases without PVL were control group. The mean gestational age(30.6±2.0) w in PVL group were significant lower than control group(31.9±2.1) w(P 0.05),the first pH value within six hours after life was also significant lower than control group(7.20±0.08 vs 7.25±0.06,P 0.05).The incidence of PVL in premature infants with intracranial hemorrhage(ICH) was significant higher than preterm infants without ICH(70.0%vs 23.7%, P 0.05),and meanwhile incidence of PVL in preterm infants with ventilator is also significant higher than preterm infants without ventilator(58.3%vs 24.6%,P 0.05).Multivariate Logistic regression revealed that the first low pH value within six hours after birth(OR=4.395,95%CI 0-0.537) and ICH (OR=4.741,95%CI 1.188-26.644) were high risk factors for PVL(P 0.05).Conclusion The first low pH value within six hours after birth and ICH were the major risk factors for PVL." @default.
- W2391382012 created "2016-06-24" @default.
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- W2391382012 date "2010-01-01" @default.
- W2391382012 modified "2023-09-23" @default.
- W2391382012 title "Risk Factors in the development of periventricular leucomalacia in preterm infants" @default.
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