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- W2391397923 abstract "Objective To retrospective analyze the efficacy differences between linear accelerator X-ray three-dimensional conformal radiotherapy(3D-CRT) and dose boosted combined with conventional conformal gamma ray stereotactic body radiotherapy(SBRT) for advanced local pancreatic carcinoma patient.Methods A total of 40 patients with advanced local pancreatic carcinoma were enrolled,male 22,female 18,aged 46-83 years old,median age 72 years old.Among these patients 28 cases were performed by 3D-CRT(3D-CRT group),12 cases by SBRT(SBRT group).In these patients there were 6 cases of stageⅡA(T3N0),5 ofⅡB(T1-3N1) and 29 of Ⅲ(T4N0-1).Total scheduled dose was 46-50 Gy for 3D-CRT group;for SBRT group,16 Gy in 8 fractions with SBRT were boosted after 40 Gy of 3D-CRT.Results The median follow-up time was 27 months(3-44 months),the median gross target volume(GTV) and clinical target volume(CTV) of total cases were 75.3 mL(17.5-191.7 mL) and 349.7 mL(114.4-727.9 mL) respectively.The median dose was 46 Gy(18-50 Gy) for 3D-CRT group and 56 Gy(54-66 Gy) for SBRT group.The median survival time was 8.4 months(1.4-35.1 months) for all cases.The median survival time of 3D-CRT group and SBRT group were 8.2 months(1.4-21.2 months) and 17.7 months(2.9-35.1 months)(P0.05).There were no statistic differences between 2 groups in terms of side effects induced by treatments.Conclusion For advanced local pancreatic carcinoma patients,the treatment of 3D-CRT combined with gamma ray SBRT have good tolerance and the survival rate is increased,but further large scale treatments should be studied." @default.
- W2391397923 created "2016-06-24" @default.
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- W2391397923 date "2010-01-01" @default.
- W2391397923 modified "2023-09-23" @default.
- W2391397923 title "Effect of three-dimensional conformal radiotherapy or dose boosted combined with gamma ray stereotactic body radiotherapy on advanced local pancreatic carcinoma" @default.
- W2391397923 hasPublicationYear "2010" @default.
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