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- W2391402735 abstract "Objective To investigate the effects of external fixator with dynamic device under low frequency and controlled micromovement on the callus calcification and mechanical property of healing bone.MethodsForty-five sheep were performed transverse osteotomy with a gap of 2 mm on the mid-shafts of both tibias,and the hind limbs were fixed with unilateral external fixators connected to a controlled micromovement device.Ten days after osteotomy,one hind limb of each sheep was randomly selected for micromovement(30 min/d).According to different micromovement frequencies,the sheep were randomly divided into 3 groups: 0.5 Hz group,1 Hz group and 5 Hz group(n=15).The amplitude of micromovement was 0.25 mm and the micromovement stopped by the end of the fourth week postoperation.The other hind limb of each sheep was served as control group without micromovement.Morphometry of callus was done at the end of 4,6 and 9 weeks after osteotomy.Bone formation velocity,bone mineral density and biomechanical properties were compared at the end of 9 weeks.Results The areas of mineralized bone and osteoid in different miromovement groups were larger than that of control group at the end of 4,6 weeks postoperation(P0.05).However,the areas of mineralized bone increased and the areas of osteoid diminished significantly in micromovement groups compared with those of control group at the end of 9 weeks postoperation(P0.05).Bone formation velocity was faster and bone mineral density,peak loading and bending stiffness were stronger in micromovement groups compared with those of control group(P0.05).ConclusionLow frequency micromovement applied at the early stage of fracture could promote osteoid formation and mineralization,reduce the mineralized lag time and increase the bone mineral content and bending stiffness of the healing bone,promote the bone healing and improve the quality as well.A frequency of 1 Hz is optimal to produce the best results." @default.
- W2391402735 created "2016-06-24" @default.
- W2391402735 creator A5041230883 @default.
- W2391402735 date "2008-01-01" @default.
- W2391402735 modified "2023-09-27" @default.
- W2391402735 title "Experimental study on callus calcification and mechanical property of healing bone under low frequency and controlled micromovement" @default.
- W2391402735 hasPublicationYear "2008" @default.
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