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- W2391444340 abstract "Objective: To investigate the correlation between Cho/Cr value of 1H magnetic resonance spectroscopy(1H-MRS) and the Ki-67 labeling index in meningiomas. Methods: Thirty-six patients with meningioma underwent conventional MR and 1H-MRS before operation (Grade I 30 cases; Grade Ⅱ+Ⅲ 6 cases). 1H-MRS sequences included PRESS 35,PRESS 144. Ex-pression of Ki-67 nuclear antigen were detected by immunohistochemical method of streptavidin-biotin-peroxidase(SP). Results: The mean Cho/Cr ratio in the benign and malignant groups were 3.80±1.08 and 7.22±0.70,respectively(t=7.40,P=0.000). Ki-67 in the benign and malignant groups were 6.43±1.09 and 12.15±4.14,respectively. A significant linear correlation was ob-served between the Cho/Cr ratio and the expression of Ki-67. The MRS features of meningiomas were as follow: Cho in-creased markedly,Cr decreased evidently. Conclusion: 1H-MRS is a useful diagnostic method for determining the proliferation or malignant potential of meningiomas according to the Cho/Cr ratio and the latter is correlated to the Ki-67 value." @default.
- W2391444340 created "2016-06-24" @default.
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- W2391444340 date "2008-01-01" @default.
- W2391444340 modified "2023-09-24" @default.
- W2391444340 title "Correlation study between Cho/Cr value of MRS and Ki-67 labeling index in meningiomas" @default.
- W2391444340 hasPublicationYear "2008" @default.
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