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- W2391465277 abstract "Objective To investigate the clinical and serological features of Sj?grens syndrome in both sex,so as to find out the clinical and serologi-cal differences between male and female cases of Sj?grens syndrome,which can benefit to the clinical diagnoses and pathogenesis.MethodsClini-cal and serological data of 436 SS cases were analyzed retrospectively.ResultsNo significant difference was found between male and female inmean age of onset and average disease duration at the time of diagnosis. Compared with female patients,dry mouth and dry eyes were less frequent inmale(P 0.05). The frequency of extra- glandular manifestations especially pulmonary interstitial fibrosis and lymphadenectasis were higher inmale than in female(P 0.05). The incidence of positive anti SSA antibodies,anti-SSB antibodies,anti nuclear antibody(ANA)and anti mito-chondrial antibody(AMA)were lower than in male in female(P 0.05).ConclusionFor male SS patient,the glandular manifestations appearedlater and milder,but extra-glandular manifestations are more common. The incidence of positive antibodies are lower in male than in female. The dif-ference between male and female cases of Sj?grens syndrome in clinical and serological features reveal that the SS patients had abnormal sex hor-mone levels,which may involved in the pathogenesis of SS." @default.
- W2391465277 created "2016-06-24" @default.
- W2391465277 creator A5056279785 @default.
- W2391465277 date "2014-01-01" @default.
- W2391465277 modified "2023-09-28" @default.
- W2391465277 title "Clinical and Serological Differences between Male and Female Cases of Sjgreńs Syndrome" @default.
- W2391465277 hasPublicationYear "2014" @default.
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