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- W2391469727 abstract "Objective To study the change in telomerase activity during proliferation inhibition of leukemia K562 cells induced by orpiment nanoparticles and further explore the molecular mechanism of the antitumor effect of orpiment nanoparticles.Methods Methyl thiazolyl tetrazolium(MTT) assay examines the growth inhibition induced by orpiment nanoparticles in vitro.TRAP-PAGE silver stain technique was performed to detect the telomerase activity of K562 cells treated with orpiment nanoparticles for 48 hours,compared with that treated with traditional orpiment at the same time.Results Orpiment nanoparticles significantly inhibited the telomerase activity of K562 cells,with a much better effect than that of traditional orpiment.Conclusions Orpiment nanoparticles can inhibit the telomerase activity of K562 cells,which may be one of important mechanisms in the anticancer effect of orpiment nanoparticles." @default.
- W2391469727 created "2016-06-24" @default.
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- W2391469727 date "2007-01-01" @default.
- W2391469727 modified "2023-09-24" @default.
- W2391469727 title "Effect of Orpiment Nanoparticles on Telomerase Activity in K562 Cell Line" @default.
- W2391469727 hasPublicationYear "2007" @default.
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