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- W2391552829 abstract "【Objective】α-2,3-sialic acid is thought to mediate IBV cells infection as an important cell surface receptor.Chicken tracheal epithelial cells(CTECs)contain at least ciliated cells,goblet cells and basal cells e.g.,andα-2,3-sialic acid receptors are not present on basal cells surface,and therefore directly in vitro studies characteristics of basal cells by IBV infection which helps to further clarify theα-2,3-sialic acid receptor relationship with IBV infection.【Method】Using optical microscopy,electron microscopy and RT-PCR method,basal cells and CTECs infected separately by IBV-M41strain was observed and detected to explore characteristics of basal cells of IBV infection.【Result】In contrast to tracheal epithelial cells infection,basal cells cultured alone infected by IBV,had no obvious morphological damage,subcellular structure(lysosome,nucleus)damages,and no IBV in the cells.【Conclusion】The tracheal epithelial cells can be infected by IBV,but basal cells alone cannot be infected,which suggested that the subsets of CTECs for IBV infection are heavily dependent on whetherα-2,3-sialic acid receptor is present on cell surface." @default.
- W2391552829 created "2016-06-24" @default.
- W2391552829 creator A5062698536 @default.
- W2391552829 date "2014-01-01" @default.
- W2391552829 modified "2023-09-25" @default.
- W2391552829 title "Research on the characteristics of basal cells of chicken trachea epithelium cells infected by IBV" @default.
- W2391552829 hasPublicationYear "2014" @default.
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