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- W2391574993 abstract "OBJECTIVE:To evaluate the effects of prophylactic application of antibiotics in hip replacement in orthopedics department of our hospital,and to gradually expand antibiotics rectification and set up a long-term management mechanism.METHODS:182 cases of hip replacement were collected,among which there were 90 cases during Apr. 2010-Apr. 2011(before rectification)and 92 cases during Nov. 2011-Nov.2012(after rectification). The natural condition of patients,varieties of antibiotics, medication timing,treatment course and so on were summarized and evaluated. The results were analyzed statistically using SPSS 18.0 software. The prophylactic use rationality of antibiotics was compared between 2 groups.RESULTS:After antibiotics special rectification,the prophylactic application of antibiotics were first-generation cephalosporins(54.35%)replacing of third-generation cephalosporins(31.11%);utilization rate of drugs were decreased significantly(P0.01);antibiotics were used 0.5-2 h before incision(88.04%)instead of 2 h before operation(58.89%);treatment course lasted for(4.07±2.32)days instead of(11.91± 3.87)days;average cost of antibiotics decreased by 71.06%. After special rectification,irrational selection of drugs,irrational preoperative medication,irrational drug replacement and irrational drug combination were decreased significantly(P0.01).CONCLUSIONS:After antibiotics special rectification,prophylactic application of antibiotics in hip replacement has been improved significantly;long-term management mechanism on the rationality of antibiotics use has been gradually established." @default.
- W2391574993 created "2016-06-24" @default.
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- W2391574993 date "2014-01-01" @default.
- W2391574993 modified "2023-09-23" @default.
- W2391574993 title "Clinical Evaluation of Prophylactic Application of Antibiotics in Hip Replacement in Orthopedics Department of Our Hospital during 2 Years" @default.
- W2391574993 hasPublicationYear "2014" @default.
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