Matches in SemOpenAlex for { <https://semopenalex.org/work/W2391625343> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2391625343 abstract "Objective:To establish a HPLC/MS/MS method for the determination of blood- remifentanil concentration. Methods:The blood samples extracted with 1-chlorobutane were separated over an Intersil ODS-3 column (50 mm×2.1 mm, 3μm) and the mobile phase consisted of a mixture of acetonitrile: chloroform (1: 1, v: v) containing ammonium acetate in concentration of 2 mmol·L-1.The flow rate was 0. 3 mL·min-1.The fentanyl citrate was used as an internal standard. The triple quadrupole mass spectrometer with the turbo ion spray interface was operated in the positive ion mode and the temperature of the turbo was set at 200℃. The ionization voltage was 5 000 V. The multi-reaction monitoring (MRM) mode was employed to scan the ions. The selected ions (precursor-ion/product-ion) were 377/228 for remifentanil and 337/188 for fentanyl. Results:The calibration linear range of blood-remifentanil concentrations was 0. 5～50 ng·mL-1(r =0. 999 4). The between-day and within-day RSD% were less than 15% . The extraction recoveries were more than 67. 3% and the method recoveries were between 95. 0% and 97. 6% . Conclusion:This rapid, sensitive and reliable HPLC/MS/MS method can be applied to monitor blood-remifentanil profile." @default.
- W2391625343 created "2016-06-24" @default.
- W2391625343 creator A5001856496 @default.
- W2391625343 date "2006-01-01" @default.
- W2391625343 modified "2023-09-28" @default.
- W2391625343 title "Determination of remifentanil in human blood by HPLC/MS/MS" @default.
- W2391625343 hasPublicationYear "2006" @default.
- W2391625343 type Work @default.
- W2391625343 sameAs 2391625343 @default.
- W2391625343 citedByCount "0" @default.
- W2391625343 crossrefType "journal-article" @default.
- W2391625343 hasAuthorship W2391625343A5001856496 @default.
- W2391625343 hasConcept C103232671 @default.
- W2391625343 hasConcept C113196181 @default.
- W2391625343 hasConcept C119128265 @default.
- W2391625343 hasConcept C145148216 @default.
- W2391625343 hasConcept C162356407 @default.
- W2391625343 hasConcept C172493649 @default.
- W2391625343 hasConcept C178790620 @default.
- W2391625343 hasConcept C179998833 @default.
- W2391625343 hasConcept C185592680 @default.
- W2391625343 hasConcept C23531484 @default.
- W2391625343 hasConcept C2776277131 @default.
- W2391625343 hasConcept C2778891214 @default.
- W2391625343 hasConcept C2781072394 @default.
- W2391625343 hasConcept C31827203 @default.
- W2391625343 hasConcept C42219234 @default.
- W2391625343 hasConcept C43617362 @default.
- W2391625343 hasConcept C71043704 @default.
- W2391625343 hasConcept C71924100 @default.
- W2391625343 hasConceptScore W2391625343C103232671 @default.
- W2391625343 hasConceptScore W2391625343C113196181 @default.
- W2391625343 hasConceptScore W2391625343C119128265 @default.
- W2391625343 hasConceptScore W2391625343C145148216 @default.
- W2391625343 hasConceptScore W2391625343C162356407 @default.
- W2391625343 hasConceptScore W2391625343C172493649 @default.
- W2391625343 hasConceptScore W2391625343C178790620 @default.
- W2391625343 hasConceptScore W2391625343C179998833 @default.
- W2391625343 hasConceptScore W2391625343C185592680 @default.
- W2391625343 hasConceptScore W2391625343C23531484 @default.
- W2391625343 hasConceptScore W2391625343C2776277131 @default.
- W2391625343 hasConceptScore W2391625343C2778891214 @default.
- W2391625343 hasConceptScore W2391625343C2781072394 @default.
- W2391625343 hasConceptScore W2391625343C31827203 @default.
- W2391625343 hasConceptScore W2391625343C42219234 @default.
- W2391625343 hasConceptScore W2391625343C43617362 @default.
- W2391625343 hasConceptScore W2391625343C71043704 @default.
- W2391625343 hasConceptScore W2391625343C71924100 @default.
- W2391625343 hasLocation W23916253431 @default.
- W2391625343 hasOpenAccess W2391625343 @default.
- W2391625343 hasPrimaryLocation W23916253431 @default.
- W2391625343 hasRelatedWork W2349411045 @default.
- W2391625343 hasRelatedWork W2352912951 @default.
- W2391625343 hasRelatedWork W2354624023 @default.
- W2391625343 hasRelatedWork W2355951513 @default.
- W2391625343 hasRelatedWork W2358291705 @default.
- W2391625343 hasRelatedWork W2359659636 @default.
- W2391625343 hasRelatedWork W2364029711 @default.
- W2391625343 hasRelatedWork W2364667144 @default.
- W2391625343 hasRelatedWork W2365651199 @default.
- W2391625343 hasRelatedWork W2366576673 @default.
- W2391625343 hasRelatedWork W2369719958 @default.
- W2391625343 hasRelatedWork W2373138742 @default.
- W2391625343 hasRelatedWork W2374923348 @default.
- W2391625343 hasRelatedWork W2381702567 @default.
- W2391625343 hasRelatedWork W2388589592 @default.
- W2391625343 hasRelatedWork W2388747213 @default.
- W2391625343 hasRelatedWork W2390866191 @default.
- W2391625343 hasRelatedWork W2979214670 @default.
- W2391625343 hasRelatedWork W3031474611 @default.
- W2391625343 hasRelatedWork W8180832 @default.
- W2391625343 isParatext "false" @default.
- W2391625343 isRetracted "false" @default.
- W2391625343 magId "2391625343" @default.
- W2391625343 workType "article" @default.