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- W2391648166 abstract "Objective To study the protective effect and its mechanism of Yulangsan polysaccharide(YLS) on primary cultured rat hepatocytes injury induced by H2O2.Methods The primary rat hepatocytes were isolated by perfusion with IV collaganase and injured by H2O2.The contents of malondialdehyde(MDA) and glutathion(GSH) in hepatocytes and the levels of AST and ALT in cultural supernatant were determined by general methods.Cell viability was assayed by MTT method.Results The elevation of MDA content in hepatocytes and AST and ALT levels in supernatant of cultural hepatocytes,and the decrease in cell viability and GSH content induced by H2O2 were restored remarkably by the treatment with YLS(0.125~1 mg/ml).Conclusion The results suggest that YLS possesses direct protective action on primary hepatocyte injury induced by H2O2.This might be associated with the anti-oxidative activity of YLS." @default.
- W2391648166 created "2016-06-24" @default.
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- W2391648166 date "2007-01-01" @default.
- W2391648166 modified "2023-09-26" @default.
- W2391648166 title "Protective Effects of Yulangsan Polysaccharide(YLS) on Primary Cultured Rat Hepatocytes Injury Induced by H_2O_2" @default.
- W2391648166 hasPublicationYear "2007" @default.
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