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- W2391706415 abstract "Objective To select the best combination doses for compound dealcoholization prescription and its components by building up model of acute alcoholic intoxication.Methods 40 mice were divided into model control group,puerana flowers group,hovenia dulcis thunb group and sodium ferulate group randomly with 10 mice in each group.Distilled spirits were administered to all mice with the dosage of 0.24 ml/10 g.Thirty minutes later,50% puerana flowers,50% hovenia dulcis thunb and 0.5% sodium ferulate were administered in each group with the dosage of 0.2 ml/10 g,respectively.The durations of the drinking mice's gait,disappearance of righting reflex and the recovery of righting reflex were investigated.The best combination dose was selected by orthogonal experiment.Results The durations of the drinking mice's gait and disappearance of righting reflex in puerana flowers group and hovenia dulcis thunb group were longer than those of the model group(P0.05).The duration of the recovery of righting reflex was shorter than that of the model group(P0.05).The results of the sodium ferulate group were not significantly different from those of the model group(P0.05).F values of puerana flowers group,hovenia dulcis thunb group and sodium ferulate group were 0.034,0.016 and 0.003,respectively.Meanwhile,0.006,0.003,and 0.032 were the F values for puerana flowers plus hovenia dulcis thunb,puerana flowers plus sodium ferulate,and hovenia dulcis thunb plus sodium ferulate,respectively.Conclusion Both puerana flowers and hovenia dulcis thunb can prolong endure-time before intoxication and shorten last-time after intoxication.The best combination dose is puerana flowers(5 g/kg) plus hovenia dulcis thunb(5 g/kg) plus sodium ferulate(50 mg/kg)." @default.
- W2391706415 created "2016-06-24" @default.
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- W2391706415 date "2009-01-01" @default.
- W2391706415 modified "2023-09-27" @default.
- W2391706415 title "Combination Analysis of Compound Dealcoholization Prescription" @default.
- W2391706415 hasPublicationYear "2009" @default.
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