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• W2391707699 abstract "The effects of metronidazole in vivo were studied on the ConA and LPS response of chick peripheral blood lymphocyte(PBL), on the IL2 activity of PBL induced by ConA, on the antibody response to two thymus dependent antigens SRBC and BSA, and to a thymus independent antigen Brucella abortus(BA) and on theproductionof complement of dexamethasonetreated chicks. The results indicated that dexamethasone treatment had no effects on the ConA and LPS response of chick PBL. It was shown that metronidazole at dose of 10 mg/kg could significantly antagonize the inhibition of dexamethasone on the IL2 activity of PBL induced by ConA, reverse the suppression of dexamethasone on antibody responses to SRBC, BSA, and BA, block the negative effects of dexamethasone on the production of complement. Levamisole had very similar effects like metronidazole in antagonizing the negative effects of dexamethasone on the immune function of chicks. It was observed that levamisole at a dose of 10 mg/kg could significantly antagonize the inhibition of dexamethasone on the IL2 activity of PBL, on antibody responses to SRBC, BSA and BA, and on the production of complement,respectively." @default.
• W2391707699 created "2016-06-24" @default.
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• W2391707699 date "2003-01-01" @default.
• W2391707699 modified "2023-09-25" @default.
• W2391707699 title "In vivo effects of metronidazole on the immunity function of dexamethasone-treated chicks" @default.
• W2391707699 hasPublicationYear "2003" @default.
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