Matches in SemOpenAlex for { <https://semopenalex.org/work/W2391738188> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2391738188 abstract "Objective To investigate the association between N-acetyltransferase2(NAT2) 7 functional SNPs and lung cancer genetic susceptibility.Methods Venous blood samples of 507 healthy controls and 500 lung cancer patients were collected,and genomic DNA was extracted.Illumina genotyping method was used to determined the genotype of NAT2.The genotyping results were analysed with statistic methods.Results Both rs 7832071 allele T and rs1208(lys263arg) allele G increased the risk of lung cancer(OR=1.49, 95%CI 1.04-2.13;OR=1.76,95%CI 1.21-2.55).According to their positions in mRNA,we inferred that rs1208 might be one of the real risk SNPs in NAT2.Stratified analysis according to the smoking status proved that rs7832071、rs1208 could increase the risk of lung cancer in current smoker(OR=1.48,95%CI 1.03-2.15;OR=2.20,95%CI 1.05-4.62).Conclusion NAT2 rs1208(lys263arg) may be one of the lung cancer risk SNPs." @default.
- W2391738188 created "2016-06-24" @default.
- W2391738188 creator A5062040281 @default.
- W2391738188 date "2006-01-01" @default.
- W2391738188 modified "2023-09-24" @default.
- W2391738188 title "Studies on the association of NAT2 polymorphism and lung cancer genetic susceptibility" @default.
- W2391738188 hasPublicationYear "2006" @default.
- W2391738188 type Work @default.
- W2391738188 sameAs 2391738188 @default.
- W2391738188 citedByCount "0" @default.
- W2391738188 crossrefType "journal-article" @default.
- W2391738188 hasAuthorship W2391738188A5062040281 @default.
- W2391738188 hasConcept C104317684 @default.
- W2391738188 hasConcept C126322002 @default.
- W2391738188 hasConcept C135763542 @default.
- W2391738188 hasConcept C143998085 @default.
- W2391738188 hasConcept C149737253 @default.
- W2391738188 hasConcept C153209595 @default.
- W2391738188 hasConcept C180754005 @default.
- W2391738188 hasConcept C2776256026 @default.
- W2391738188 hasConcept C31467283 @default.
- W2391738188 hasConcept C54355233 @default.
- W2391738188 hasConcept C71924100 @default.
- W2391738188 hasConcept C86803240 @default.
- W2391738188 hasConceptScore W2391738188C104317684 @default.
- W2391738188 hasConceptScore W2391738188C126322002 @default.
- W2391738188 hasConceptScore W2391738188C135763542 @default.
- W2391738188 hasConceptScore W2391738188C143998085 @default.
- W2391738188 hasConceptScore W2391738188C149737253 @default.
- W2391738188 hasConceptScore W2391738188C153209595 @default.
- W2391738188 hasConceptScore W2391738188C180754005 @default.
- W2391738188 hasConceptScore W2391738188C2776256026 @default.
- W2391738188 hasConceptScore W2391738188C31467283 @default.
- W2391738188 hasConceptScore W2391738188C54355233 @default.
- W2391738188 hasConceptScore W2391738188C71924100 @default.
- W2391738188 hasConceptScore W2391738188C86803240 @default.
- W2391738188 hasLocation W23917381881 @default.
- W2391738188 hasOpenAccess W2391738188 @default.
- W2391738188 hasPrimaryLocation W23917381881 @default.
- W2391738188 hasRelatedWork W1965576720 @default.
- W2391738188 hasRelatedWork W1972987358 @default.
- W2391738188 hasRelatedWork W2008883925 @default.
- W2391738188 hasRelatedWork W2077463202 @default.
- W2391738188 hasRelatedWork W2077895527 @default.
- W2391738188 hasRelatedWork W2096656959 @default.
- W2391738188 hasRelatedWork W2134595239 @default.
- W2391738188 hasRelatedWork W2159469480 @default.
- W2391738188 hasRelatedWork W2229609488 @default.
- W2391738188 hasRelatedWork W2237396639 @default.
- W2391738188 hasRelatedWork W2263513184 @default.
- W2391738188 hasRelatedWork W2361928548 @default.
- W2391738188 hasRelatedWork W2374112823 @default.
- W2391738188 hasRelatedWork W2377612944 @default.
- W2391738188 hasRelatedWork W28571663 @default.
- W2391738188 hasRelatedWork W2912603490 @default.
- W2391738188 hasRelatedWork W3010779551 @default.
- W2391738188 hasRelatedWork W3028767506 @default.
- W2391738188 hasRelatedWork W3090005840 @default.
- W2391738188 hasRelatedWork W3092429121 @default.
- W2391738188 isParatext "false" @default.
- W2391738188 isRetracted "false" @default.
- W2391738188 magId "2391738188" @default.
- W2391738188 workType "article" @default.