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- W2391780504 abstract "To observe the change of thrombomodulin and its relationship with TNF-α in acute cerebral infarct wiht HAP Methods:The patients wiht acute cerebral infarct were divided into the group A (n=24)of pure infarct and the group B (n=16) of acute infarc with HAP,with mormal control (n=13). The serum samples were obtained from 1d to 21d after infarct . The serum level of thrombomodulin and TNF-α were examinde by ELISA method and radioimmunjoassay respec-tivel. Results:The serum levels of thrombomodulin of the group B were significantly lower than those of the group Ain the first week and 14d after infarct (P0. 05),with similar result at 21d. The serum levels of TNF-a of the group B were singificantly higher than those of the group A from the first week to 21d after infarct (P0. 05) .although HAP had been prohibited in 21d. In the group of acute infarct with HAP the serum levels of thrombomodulin reated inversely with the serum levels of TNF-α . Therelationship between thrombomodulin and TNF-α compromised with Gompertz curve. Conclusions; It's posible that the increase of serum TNF-α in acute infarct with HAP may injury the endotheliocyte of brain vessel and prohibited the anticoagulative system,presenting with downregulation of the level of serum thrombomodulin." @default.
- W2391780504 created "2016-06-24" @default.
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- W2391780504 date "2004-01-01" @default.
- W2391780504 modified "2023-09-24" @default.
- W2391780504 title "The relationship between serum thrombomodulin and serum TNF-αin actute cerebral infarct with HAP" @default.
- W2391780504 hasPublicationYear "2004" @default.
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